Jul 8, 2014, 12:23 PM
News Code: 2720630
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Iranian nanocarriers facilitate controlled drug delivery

Tehran, July 8, IRNA - Researchers at Amirkabir University of Technology have developed nanocarriers, which encapsulate a large amount of drug for controlled drug delivery.

Mohammad Mehdi Hassani-Sadrabadi, Faramarz Afshar-Taromi and Hamid Mirzadeh, faculty members of the university, and Vahid Karimkhani were researchers of the study, the English-language paper 'Iran Daily' said on Tuesday.

Microfluidic platform for the synthesis of complex nanocapsules was presented via a controlled self-assembly.

The monodisperse nanocapsules in the range of 50–200 nm consist of a dendritic polyethylene core and a pluronic copolymer shell.

The resultant nanocarriers encapsulate a large amount of hydrophobic anticancer drug like paclitaxel while providing a low complement activation as well as sustained release profile with high tuning.